Using Big Data for LC-MS/MS Quality Analysis

Article for Clinical Laboratory News written by ADAM ZABELL, PHD & Business Analyst at Indigo BioAutomation JUDITH STONE, PhD, and RANDALL K. JULIAN, PhD 

In addition to its impressive sensitivity, liquid chromatography-tandem­ mass spectrometry (LC-MS/MS) analysis brings the advantage of automatic metadata collection. This analytic information about the observed peak gives labs insight into performance of the chromatography, MS, sample preparation, and usually some combination of all three. Ultimately, laboratories use metadata to decide whether a result is reportable or needs further investigation.