Article for Today’s Clinical Lab written by ADAM ZABELL, PHD & Business Analyst at Indigo BioAutomation
LC-MS/MS in the clinical laboratory delivers a powerful instrument with the ability to separate analytes of interest on orthogonal technology (chromatography and mass spectrometry), deliver on a wide selection of sample preparation and chromatography chemistries, and selectively identify species by their mass. Coupled with a wide quantitative range and minimal sample volume, these devices are especially attractive when developing an assay not otherwise available on the commercial market. Effective quality rules are a critical component in LC-MS/MS to manage this complexity.